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Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver
- Source :
- European Journal of Radiology. 81:2450-2455
- Publication Year :
- 2012
- Publisher :
- Elsevier BV, 2012.
-
Abstract
- Purpose To clarify the optimal iodine dose of contrast material for 3-dimensional multidetector-row CT angiography (3D-MDCTA) of the venous vasculature of the liver using volume rendering technique. Materials and methods This study included 103 patients who were randomly assigned to 5 contrast-enhanced MDCT protocol groups with different body-weight-tailored doses of contrast material: 500, 600, 630, 650, and 700 mgI/kg body weight. The arterial, portal, and hepatic parenchymal phases were obtained to evaluate enhancement values of the aorta, portal vein, and hepatic vein. Visualization of the portal and hepatic veins on the volume-rendering images of 3D-MDCTA was evaluated using a 5-point grade. Dunnett's test was used to compare the mean enhancement value and mean grades of image quality (700 mgI/kg dose group was control). Results The mean enhancement values of portal and hepatic vein in the group with 500 and 600 mgI/kg were significantly lower than those of the control group. During visual assessment, a significantly lower mean grades were observed in 500 mgI/kg groups for the portal vein, and 500 and 600 mgI/kg groups for hepatic vein. There were no significant intergroup differences in mean enhancement values and visual assessment among the groups using 630 mgI/kg or more. Conclusion Iodine doses of 630 mgI/kg was recommended for 3D-MDCTA.
- Subjects :
- Male
medicine.medical_specialty
Portal vein
Contrast Media
chemistry.chemical_element
Hepatic Veins
Iodine
Body weight
Sensitivity and Specificity
Imaging, Three-Dimensional
medicine.artery
Dose group
medicine
Humans
Radiology, Nuclear Medicine and imaging
Vein
Aorta
Dose-Response Relationship, Drug
medicine.diagnostic_test
business.industry
Reproducibility of Results
Phlebography
General Medicine
Middle Aged
Iopamidol
Radiographic Image Enhancement
medicine.anatomical_structure
chemistry
Hepatic veins
Angiography
Female
Radiology
Tomography, X-Ray Computed
Nuclear medicine
business
Subjects
Details
- ISSN :
- 0720048X
- Volume :
- 81
- Database :
- OpenAIRE
- Journal :
- European Journal of Radiology
- Accession number :
- edsair.doi.dedup.....51e6eb1441ee82439db72a8d19bef21b