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Dynamics of the Cognitive Procedural Learning in Alcoholics with Korsakoff's Syndrome
- Source :
- Alcoholism: Clinical and Experimental Research, Alcoholism: Clinical and Experimental Research, Wiley, 2013, 37 (6), pp.1025-1032. ⟨10.1111/acer.12054⟩, Alcoholism: Clinical and Experimental Research, 2013, 37 (6), pp.1025-1032. ⟨10.1111/acer.12054⟩
- Publication Year :
- 2013
- Publisher :
- HAL CCSD, 2013.
-
Abstract
- Background While procedures acquired before the development of amnesia are likely to be preserved in alcoholic patients with Korsakoff's syndrome, the ability of Korsakoff patients (KS) to learn new cognitive procedures is called in question. According to the Adaptive Control of Thoughts model, learning a new cognitive procedure requires highly controlled processes in the initial cognitive phase, which may be difficult for KS with episodic and working memory deficits. The goals of the present study were to examine the learning dynamics of KS compared with uncomplicated alcoholic patients (AL) and control subjects (CS) and to determine the contribution of episodic and working memory abilities in cognitive procedural learning performance. Methods Fourteen KS, 15 AL, and 15 CS were submitted to 40 trials (4 daily learning sessions) of the Tower of Toronto task (disk-transfer task similar to the tower of Hanoi task) as well as episodic and working memory tasks. Results The 10 KS who were able to perform the cognitive procedural learning task obtained lower results than both CS and AL. The cognitive phase was longer in the Korsakoff's syndrome group than in the other 2 groups but did not differ between the 3 groups any more when episodic memory abilities were controlled. Conclusions Our results indicate that KS have impaired cognitive procedural learning abilities compared with both AL and CS. Episodic memory deficits observed in KS result in a delayed transition from the cognitive learning phase to more advanced learning phases and, as a consequence, in an absence of automation of the procedure within 40 trials.
- Subjects :
- Male
Reconstructive memory
Memory, Episodic
[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
[SDV.NEU.PC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior
Medicine (miscellaneous)
Amnesia
Neuropsychological Tests
Toxicology
050105 experimental psychology
Procedural memory
03 medical and health sciences
0302 clinical medicine
Alcohol Amnestic Disorder
medicine
Humans
Learning
0501 psychology and cognitive sciences
Cognitive skill
Episodic memory
ComputingMilieux_MISCELLANEOUS
[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior
Working memory
[SCCO.NEUR]Cognitive science/Neuroscience
05 social sciences
[SCCO.NEUR] Cognitive science/Neuroscience
Cognition
Middle Aged
medicine.disease
Psychiatry and Mental health
Alcoholism
Memory, Short-Term
Case-Control Studies
[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health
[SCCO.PSYC] Cognitive science/Psychology
[SCCO.PSYC]Cognitive science/Psychology
Female
medicine.symptom
Korsakoff's syndrome
Psychology
030217 neurology & neurosurgery
Cognitive psychology
Subjects
Details
- Language :
- English
- ISSN :
- 01456008 and 15300277
- Database :
- OpenAIRE
- Journal :
- Alcoholism: Clinical and Experimental Research, Alcoholism: Clinical and Experimental Research, Wiley, 2013, 37 (6), pp.1025-1032. ⟨10.1111/acer.12054⟩, Alcoholism: Clinical and Experimental Research, 2013, 37 (6), pp.1025-1032. ⟨10.1111/acer.12054⟩
- Accession number :
- edsair.doi.dedup.....524991e3fc868f582e002f1b9cc85ad1