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Sarco-Model: A score to predict the dropout risk in the perspective of organ allocation in patients awaiting liver transplantation
- Publication Year :
- 2021
-
Abstract
- BACKGROUND & AIMS Sarcopenia in liver transplantation (LT) cirrhotic candidates has been connected with higher dropouts and graft losses after transplant. The study aims to create an 'urgency' model combining sarcopenia and Model for End-stage Liver Disease Sodium (MELDNa) to predict the risk of dropout and identify an appropriate threshold of post-LT futility. METHODS A total of 1087 adult cirrhotic patients were listed for a first LT during January 2012 to December 2018. The study population was split into a training (n = 855) and a validation set (n = 232). RESULTS Using a competing-risk analysis of cause-specific hazards, we created the Sarco-Model2 . According to the model, one extra point of MELDNa was added for each 0.5 cm2 /m2 reduction of total psoas area (TPA)
- Subjects :
- MELDNa
Adult
Liver Cirrhosis
Futile transplant
medicine.medical_specialty
futility
Sarcopenia
Cirrhosis
Waiting Lists
medicine.medical_treatment
Settore MED/18 - CHIRURGIA GENERALE
Allocation
Futility
malnutrition
Liver transplantation
Liver Transplant
dropout
Severity of Illness Index
sarcopenia
End Stage Liver Disease
03 medical and health sciences
Liver disease
0302 clinical medicine
allocation
Internal medicine
medicine
Humans
Dropout (neural networks)
Outcome
Hepatology
business.industry
cirrhosis
Area under the curve
Score
Prognostic Index
medicine.disease
Prognosis
MELD
Liver Transplantation
Transplantation
030220 oncology & carcinogenesis
Population study
030211 gastroenterology & hepatology
adult
humans
liver cirrhosis
prognosis
severity of illness index
waiting lists
end stage liver disease
liver transplantation
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....5254ea37e34229798183c93527edb07d