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Iron deficiency in Russia heart failure patients. Observational cross-sectional multicenter study

Authors :
V. Yu. Mareev
Yu. L. Begrambekova
Yu. V. Mareev
Zh. D. Kobalava
L. V. Karapetyan
S. A. Galochkin
E. R. Kazakhmedov
A. A. Lapshin
A. A. Garganeeva
E. A. Kuzheleva
A. А. Efremushkina
E. V. Kiseleva
O. L. Barbarash
T. B. Pecherina
A. S. Galyavich
Z. M. Galeeva
L. V. Baleeva
N. A. Koziolova
A. S. Veklich
D. V. Duplyakov
M. N. Maksimova
S. S. Yakushin
E. A. Smirnova
E. V. Sedykh
I. I. Shaposhnik
N. A. Makarova
A. A. Zemlyanukhina
V. V. Skibitsky
A. V. Fendrikova
A. V. Skibitsky
N. A. Spiropulos
E. M. Seredenina
Ya. A. Orlova
K. A. Eruslanova
Yu. V. Kotovskaya
O. N. Tkacheva
M. A. Fedin
Source :
Kardiologiia. 62:4-8
Publication Year :
2022
Publisher :
APO Society of Specialists in Heart Failure, 2022.

Abstract

Aim To evaluate the prevalence of iron deficiency (ID) in Russian patients with heart failure (HF).Material and methods Iron metabolism variables were studied in 498 (198 women, 300 men) patients with HF. Data were evaluated at admission for HF (97 %) or during an outpatient visit (3 %). ID was determined according to the European Society of Cardiology Guidelines.Results 83.1 % of patients had ID; only 43.5 % of patients with ID had anemia. Patients with ID were older: 70.0 [63.0;79.0] vs. 66.0 years [57.0;75.2] (p=0.009). The number of patients with ID increased in parallel with the increase in HF functional class (FC). Among patients with ID, fewer people were past or current alcohol users (p=0.002), and a greater number of patients had atrial fibrillation (60.1 vs. 45.2 %, p=0.016). A multiple logistic regression showed that more severe HF (HF FC) was associated with a higher incidence of ID detection, whereas past alcohol use was associated with less pronounced ID. An increase in N-terminal pro-brain natriuretic peptide (NT-proBNP) by 100 pg/ml was associated with an increased likelihood of ID (odds ratio, 1.006, 95 % confidence interval: 1.002–1.011, p=0.0152).Conclusion The incidence rate of HF patients is high in the Russian Federation (83.1 %). Only 43.5 % of these patients had anemia. The prevalence of ID in the study population increased with increases in HF FC and NT-proBNP.

Details

ISSN :
24125660 and 00229040
Volume :
62
Database :
OpenAIRE
Journal :
Kardiologiia
Accession number :
edsair.doi.dedup.....529efb4adb415e821bfa226f23173583