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Sperm DNA fragmentation index does not correlate with blastocyst euploidy rate in egg donor cycles

Authors :
Nancy Li
Noga Fuchs Weizman
Clifford Librach
Khaled Zohni
Ran Antes
Natalia Yasovich
Valeriy Kuznyetsov
Itai Gat
Source :
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 34(3)
Publication Year :
2017

Abstract

Sperm DNA fragmentation is a known etiology for male infertility. We evaluated the impact of sperm DNA fragmentation index (DFI) on blastocyst euploidy in IVF cycles with egg donors. This observational retrospective study, which was conducted in a university affiliated fertility clinic, included IVF-ICSI-pre-implantation Genetic Screening (PGS) egg donor cycles in which DFI was tested prior to IVF, between January 1st, 2014 and July 31st, 2016. Twenty-seven cycles with DFI 15% were included in the study group and compared with 18 cycles of DFI 15% within control group. Research group participants had significantly lower sperm count and motility (55.4*10

Details

ISSN :
14730766
Volume :
34
Issue :
3
Database :
OpenAIRE
Journal :
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Accession number :
edsair.doi.dedup.....5325c87a047ba10b6f268694d41c3c65