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Post-vaccination SARS-CoV-2 antibody kinetics and protection duration against Omicron in elderly population
- Source :
- Journal of Infection, Journal of Infection, 2022, 85 (6), pp.702-769. ⟨10.1016/j.jinf.2022.08.040⟩
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- International audience; Coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 is particularly severe in older individuals because of an impaired immune response.1 The vaccines presently available are less efficacious in older individuals, because of the senescence of their immune systems.2 A recent letter in Journal of Infection showed the need of a third vaccine dose due to a waning antibody response against new SARS-CoV-2 variants in healthy and immunocompromised individuals.3 In this study, we analysed the protection against Omicron provided by the immune responses of nursing home residents (NHRs) and a population of healthcare workers (HCWs).
- Subjects :
- MESH: Aged
Microbiology (medical)
[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology
MESH: COVID-19* / prevention & control
MESH: Kinetics
SARS-CoV-2
Vaccination
COVID-19
MESH: Vaccination
Antibodies, Viral
Kinetics
Infectious Diseases
MESH: SARS-CoV-2
Humans
MESH: Antibodies, Viral
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Aged
Subjects
Details
- ISSN :
- 01634453
- Volume :
- 85
- Database :
- OpenAIRE
- Journal :
- Journal of Infection
- Accession number :
- edsair.doi.dedup.....5329b053a07afcbe71fb3ed69445fd68