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Allergenic Properties and Molecular Characteristics of PR-1 Proteins
- Source :
- Frontiers in Allergy, Vol 3 (2022), Frontiers in allergy, 3:824717
- Publication Year :
- 2022
- Publisher :
- Frontiers Media SA, 2022.
-
Abstract
- Only a small fraction of proteins in plants and animals are classified as allergens. The allergenic properties are frequently attributed to certain functional characteristics of the proteins, such as a role in the plant defense against biotic and abiotic stress, to achieve the systematic acquired resistance. In line with this, eight members out of 17 functional pathogenesis-related (PR) protein families have been characterized as allergens. The present review summarizes the molecular features and allergenic significance of allergens of the PR-1 family. Not many allergens have been identified as belonging to this protein family, with most of them having a pollen origin, like mugwort or Bermuda grass. Molecular and structural features of allergenic PR-1 proteins are discussed and attributed to their IgE-reactive properties, clinical manifestation, and cross-reactivity among different foods and inhalants.
Details
- ISSN :
- 26736101
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Frontiers in Allergy
- Accession number :
- edsair.doi.dedup.....53dc396e8629b995edf14b3ce3700ace
- Full Text :
- https://doi.org/10.3389/falgy.2022.824717