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The intrathoracic lymph node ratio seems to be a better prognostic factor than the level of lymph node involvement in lung metastasectomy of colorectal carcinoma
- Source :
- Interactive CardioVascular and Thoracic Surgery. 20:215-221
- Publication Year :
- 2014
- Publisher :
- Oxford University Press (OUP), 2014.
-
Abstract
- OBJECTIVES Data on thoracic lymph node involvement (LNI) in lung metastasis of colorectal cancer (CRC) are conflicting, with a 5-year overall survival (OS) ranging from 6 to 40%. We aimed to evaluate whether there are subgroups of patients according to the lymph node ratio (LNR). METHODS We retrospectively reviewed the data from 106 patients who underwent a thoracic procedure for CRC lung metastasis with pathologically proven thoracic LNI. RESULTS In the univariate analysis, the median OS was significantly poorer for a pN2 location of LNI (26 vs 16 months, P = 0.04), LNR ≥50% (30 vs 17 months, P = 0.005), high preoperative CEA (32 vs 16 months, P = 0.02), hepatic metastases (27 vs 11 months, P
- Subjects :
- Male
Pulmonary and Respiratory Medicine
Oncology
medicine.medical_specialty
Lung Neoplasms
Time Factors
Colorectal cancer
Kaplan-Meier Estimate
Preoperative care
Gastroenterology
Disease-Free Survival
Predictive Value of Tests
Risk Factors
Internal medicine
medicine
Humans
Pneumonectomy
Prospective cohort study
Lymph node
Aged
Proportional Hazards Models
Retrospective Studies
Univariate analysis
business.industry
Carcinoma
Hazard ratio
Metastasectomy
Middle Aged
medicine.disease
Intrathoracic Lymph Node
Treatment Outcome
medicine.anatomical_structure
Lymphatic Metastasis
Lymph Node Excision
Female
Surgery
Lymph Nodes
Neoplasm Recurrence, Local
Colorectal Neoplasms
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15699285 and 15699293
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Interactive CardioVascular and Thoracic Surgery
- Accession number :
- edsair.doi.dedup.....53f3411c480221fed9d45d4698af8570