Supplementary Figure 4 from Modeling a Lethal Prostate Cancer Variant with Small-Cell Carcinoma Features

PDF file - 1.1MB, A, Chromosomal regions commonly amplified (red) and deleted (blue) in the SCPC/LCNEC (left panel) and adenocarcinoma (AdCa, right panel) xenografts. B, AR, cyclin D1, and RB1 promoter methylation of the AR-positive LNCaP prostate cancer cell line, the AR-negative PC-3 and DU145 prostate cancer cell lines, and the SCPC/LCNEC MDA PCa 144-4, 144-13, 146-10, and 155-2 xenografts. SCPC, small-cell prostate carcinoma; LCNEC, large-cell neuroendocrine carcinoma; AR, androgen receptor; RB, retinoblastoma.