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Massive postpartum hemorrhage associated with coagulation defect
Massive postpartum hemorrhage associated with coagulation defect
- Source :
- American Journal of Obstetrics and Gynecology. 67:349-355
- Publication Year :
- 1954
- Publisher :
- Elsevier BV, 1954.
-
Abstract
- 1. 1. Four cases of severe postpartum bleeding associated with coagulation defect are presented. 2. 2. Transient hypofibrinogenemia was present in all patients at the height of the bleeding diathesis. 3. 3. The serum of one patient showed transient but marked fibrinolytic activity. 4. 4. In two patients, transient thrombocytopenia was noted. 5. 5. Intravenous fibrinogen caused prompt return of the coagulation mechanism to normal. 6. 6. The removal of the uterus and its contents does not ensure rapid correction of the coagulation defect. Additional fibrinogen is frequently necessary. 7. 7. All patients in whom a diagnosis is made of severe toxemia of pregnancy, premature separation of the placenta, marked isoimmunization in pregnancy, presence of a dead fetus, or severe hepatic damage should be screened for the possible development of afibrinogenemia at the time of delivery.
- Subjects :
- medicine.medical_specialty
Hemorrhage
Fibrinogen
Gastroenterology
Pregnancy
Internal medicine
Placenta
medicine
Humans
Blood Coagulation
postpartum bleeding
Afibrinogenemia
business.industry
Postpartum Hemorrhage
Postpartum Period
Obstetrics and Gynecology
Blood Coagulation Disorders
Hypofibrinogenemia
medicine.disease
Surgery
Bleeding diathesis
medicine.anatomical_structure
Coagulation
Female
business
medicine.drug
Subjects
Details
- ISSN :
- 00029378
- Volume :
- 67
- Database :
- OpenAIRE
- Journal :
- American Journal of Obstetrics and Gynecology
- Accession number :
- edsair.doi.dedup.....548c5bd095ea3cb54fd6bbb70d199a47
- Full Text :
- https://doi.org/10.1016/0002-9378(54)90131-3