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Apoptosis of Purkinje and granular cells of the cerebellum following chronic ethanol intake
- Source :
- Cerebellum (London, England). 13(6)
- Publication Year :
- 2014
-
Abstract
- Ethanol alters motricity, learning, cognition, and cellular metabolism in the cerebellum. We evaluated the effect of ethanol on apoptosis in Golgi, Purkinje, and granule cells of the cerebellum in adult rats. There were two groups of 20 rats: a control group that did not consume ethanol and an experimental group of UChA rats that consumed ethanol at 10 % (
- Subjects :
- Male
Cerebellum
Cytoplasm
medicine.medical_treatment
Gene Expression
Caspase 3
Apoptosis
DNA Fragmentation
Biology
Inhibitor of apoptosis
Real-Time Polymerase Chain Reaction
Inhibitor of Apoptosis Proteins
Receptor, IGF Type 1
Microscopy, Electron, Transmission
medicine
In Situ Nick-End Labeling
Animals
Myelin Sheath
Neurons
TUNEL assay
Ethanol
Growth factor
Central Nervous System Depressants
Lipid Droplets
Molecular biology
Immunohistochemistry
XIAP
Rats
medicine.anatomical_structure
Neurology
Cerebellar cortex
Neurology (clinical)
Subjects
Details
- ISSN :
- 14734230
- Volume :
- 13
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Cerebellum (London, England)
- Accession number :
- edsair.doi.dedup.....54ce722b06ad1ccecff6b83f2fa29ede