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Longitudinal profiles of back pain across adulthood and their relationship with childhood factors: Evidence from the 1946 British birth cohort
- Source :
- Pain
- Publication Year :
- 2018
- Publisher :
- Lippincott, Williams & Wilkins, 2018.
-
Abstract
- Supplemental Digital Content is Available in the Text. In a British birth cohort study, 4 distinct long-term back pain profiles were identified, each of which was associated with different early life risk factors.<br />This study aimed to (1) characterise long-term profiles of back pain across adulthood and (2) examine whether childhood risk factors were associated with these profiles, using data from 3271 participants in the Medical Research Council National Survey of Health and Development. A longitudinal latent class analysis was conducted on binary outcomes of back pain at ages 31, 36, 43, 53, 60 to 64, and 68 years. Multinomial logistic regression models were used to examine associations between selected childhood risk factors and class membership; adjusted for sex, adult body size, health status and behaviours, socioeconomic position, and family history of back pain. Four profiles of back pain were identified: no or occasional pain (57.7%), early-adulthood only (16.1%), mid-adulthood onset (16.9%), and persistent (9.4%). The “no or occasional” profile was treated as the referent category in subsequent analyses. After adjustment, taller height at age 7 years was associated with a higher likelihood of early-adulthood only (relative risk ratio per 1 SD increase in height = 1.31 [95% confidence interval: 1.05-1.65]) and persistent pain (relative risk ratio = 1.33 [95% confidence interval: 1.01-1.74]) in women (P for sex interaction = 0.01). Factors associated with an increased risk of persistent pain in both sexes were abdominal pain, poorest care in childhood, and poorer maternal health. Abdominal pain and poorest housing quality were also associated with an increased likelihood of mid-adulthood onset pain. These findings suggest that there are different long-term profiles of back pain, each of which is associated with different early life risk factors. This highlights the potential importance of early life interventions for the prevention and management of back pain.
- Subjects :
- Adult
Male
Abdominal pain
Psychological intervention
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Back pain
medicine
Long term
Prevalence
Humans
030212 general & internal medicine
Longitudinal Studies
Family history
Exercise
Multinomial logistic regression
Aged
Family Characteristics
Anthropometry
business.industry
Middle Aged
Childhood
Latent class model
Confidence interval
United Kingdom
Anesthesiology and Pain Medicine
Neurology
Risk factors
Socioeconomic Factors
Latent Class Analysis
Relative risk
Female
Neurology (clinical)
medicine.symptom
business
030217 neurology & neurosurgery
Birth cohort
Demography
Research Paper
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Pain
- Accession number :
- edsair.doi.dedup.....558bf1876888d0cb6644fd79daa7736f