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Guided isolation of daphnane-type diterpenes from Daphne genkwa by molecular network strategies
- Source :
- Phytochemistry. 198
- Publication Year :
- 2021
-
Abstract
- A molecular networking-guided study on the Daphne genkwa Sieb. et Zucc led to the isolation of twelve daphnane-type diterpenoids including four undescribed compounds, yuanhuakines A-D. Their structures were elucidated by spectroscopic analyses, ECD calculations, and single-crystal X-ray diffraction analysis. All isolates were evaluated for their inhibitory activity against the A549, Hep3B, and MCF-7 cell lines. The majority of compounds inhibited A549 cells with IC
Details
- ISSN :
- 18733700
- Volume :
- 198
- Database :
- OpenAIRE
- Journal :
- Phytochemistry
- Accession number :
- edsair.doi.dedup.....55a1f728afe9755cc4a1a20b80cba640