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Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes
- Publication Year :
- 2023
- Publisher :
- Taylor & Francis, 2023.
-
Abstract
- The use of carbon nanotubes (CNTs) could improve medical diagnosis and treatment provided they show no adverse effects in the organism. In this study, short CNTs with different diameters with and without carboxyl surface functionalisation were assessed. After physicochemical characterisation, cytotoxicity in phagocytic and non-phagocytic cells was determined. The role of oxidative stress was evaluated according to the intracellular glutathione levels and protection by N-acetyl cysteine (NAC). In addition to this, the mode of cell death was also investigated. CNTs
- Subjects :
- Microscopy, Electron, Scanning Transmission
Small diameter
Materials science
Cell Survival
Surface Properties
Intracellular glutathione
Biomedical Engineering
Cell Culture Techniques
Nanotechnology
Apoptosis
Carbon nanotube
Toxicology
medicine.disease_cause
Article
law.invention
Cell Line
law
medicine
Animals
Humans
Particle Size
Cytotoxicity
Large diameter
Phagocytes
Dose-Response Relationship, Drug
Nanotubes, Carbon
Carbon Dioxide
Oxidative Stress
Chemical engineering
Particle size
Oxidative stress
Cysteine
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....55a326ea3fd248797a92fe1aa1b48be0
- Full Text :
- https://doi.org/10.6084/m9.figshare.21830305.v1