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The Impact of COVID-19 on Cancer Recurrence: A Narrative Review
- Source :
- Archives of Iranian Medicine. 25:450-455
- Publication Year :
- 2022
- Publisher :
- Maad Rayan Publishing Company, 2022.
-
Abstract
- Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) continues to be a worldwide healthcare problem. While our knowledge of the interaction of cancer and its management with COVID-19 mortality is gradually evolving, there are still many unanswered questions regarding the impact of COVID-19 on cancer and its prognosis. Several factors activated during COVID-19 have been implicated in tumorigenesis and the development of metastasis. Inflammation, hypoxia, reduced levels of angiotensin converting enzyme 2, elevated levels of Interleukin 6 and some other cytokines that are hallmarks of COVID-19 are capable of inducing tumor relapse and metastasis. On the other hand, there are reports that COVID-19 has been associated with cancer cure. Understanding the interaction between COVID-19 and tumor cells is essential for evaluating the potential long-term risks of COVID-19 in cancer patients, and for scheduling necessary preventive and therapeutic interventions. In this review, we briefly overview the potential impacts that COVID-19 might have on tumorigenesis and cancer relapse, as well as the role that COVID-19 might play in cancer remission and cure.
- Subjects :
- Lung Diseases
SARS-CoV-2
Recurrence
Carcinogenesis
Humans
COVID-19
General Medicine
Subjects
Details
- ISSN :
- 17353947 and 10292977
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Archives of Iranian Medicine
- Accession number :
- edsair.doi.dedup.....5632e4faef8fdc3436e968267d3e17de
- Full Text :
- https://doi.org/10.34172/aim.2022.74