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The Impact of COVID-19 on Cancer Recurrence: A Narrative Review

Authors :
Ahmad R Mafi
Ali Ghanbari Motlagh
Payam Azadeh
Source :
Archives of Iranian Medicine. 25:450-455
Publication Year :
2022
Publisher :
Maad Rayan Publishing Company, 2022.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) continues to be a worldwide healthcare problem. While our knowledge of the interaction of cancer and its management with COVID-19 mortality is gradually evolving, there are still many unanswered questions regarding the impact of COVID-19 on cancer and its prognosis. Several factors activated during COVID-19 have been implicated in tumorigenesis and the development of metastasis. Inflammation, hypoxia, reduced levels of angiotensin converting enzyme 2, elevated levels of Interleukin 6 and some other cytokines that are hallmarks of COVID-19 are capable of inducing tumor relapse and metastasis. On the other hand, there are reports that COVID-19 has been associated with cancer cure. Understanding the interaction between COVID-19 and tumor cells is essential for evaluating the potential long-term risks of COVID-19 in cancer patients, and for scheduling necessary preventive and therapeutic interventions. In this review, we briefly overview the potential impacts that COVID-19 might have on tumorigenesis and cancer relapse, as well as the role that COVID-19 might play in cancer remission and cure.

Details

ISSN :
17353947 and 10292977
Volume :
25
Database :
OpenAIRE
Journal :
Archives of Iranian Medicine
Accession number :
edsair.doi.dedup.....5632e4faef8fdc3436e968267d3e17de
Full Text :
https://doi.org/10.34172/aim.2022.74