Sulphur ylide-mediated cyclopropanation and subsequent spirocyclopropane rearrangement reactions

Authors :: Qing-Song Dai
Jun-Long Li
Qi-Wei Wang
Si-Lin Yang
Ying-Mao Tao
Mei-Hao He
Qing-Zhu Li
Bo Han
Xiang Zhang
Source :: Organic & Biomolecular Chemistry. 20:3486-3490
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: A formal (2 + 1) annulation and three-component (1 + 1 + 1) cascade cyclisation via sulphur ylide cyclopropanation under mild conditions is described, with the spiro-cyclopropyl iminoindoline moiety transformed into pyrrolo[3,4-c]quinoline through a novel rearrangement process.

Subjects :: Cyclization
Organic Chemistry
Physical and Theoretical Chemistry
Biochemistry
Sulfur

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