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Investigations in systemic vasculitis – The role of imaging
- Source :
- Best Practice & Research Clinical Rheumatology. 32:63-82
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Imaging plays an increasing role for confirming a suspected diagnosis of giant cell arteritis (GCA) or Takayasu arteritis (TAK). Ultrasound, magnetic resonance imaging (MRI), and computed tomography demonstrate a homogeneous, most commonly concentric, arterial wall thickening. 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) displays increased FDG uptake of inflamed artery walls delineating increased metabolism. Ultrasound and MRI are recommended to be the initial imaging modalities in cranial GCA and TAK, respectively. Extracranial disease can be confirmed by all four modalities, particularly by PET in case of inflammation of unknown origin. If the diagnosis remains uncertain, additional investigations including biopsy and/or additional imaging are recommended. Imaging should be performed by a trained specialist using appropriate operational procedures and settings with appropriate equipment. Further research is necessary on the role of imaging for disease monitoring. This review will discuss advantages and disadvantages of imaging modalities in the diagnosis of vasculitis.
- Subjects :
- 030203 arthritis & rheumatology
medicine.medical_specialty
medicine.diagnostic_test
business.industry
Systemic Vasculitis
Ultrasound
Magnetic resonance imaging
medicine.disease
Magnetic Resonance Imaging
030218 nuclear medicine & medical imaging
03 medical and health sciences
Giant cell arteritis
0302 clinical medicine
Rheumatology
Positron emission tomography
Positron-Emission Tomography
Biopsy
medicine
Humans
Radiology
Tomography, X-Ray Computed
Vasculitis
business
Microscopic polyangiitis
Systemic vasculitis
Subjects
Details
- ISSN :
- 15216942
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Best Practice & Research Clinical Rheumatology
- Accession number :
- edsair.doi.dedup.....56e7acc3d27b2e12ae159fbfb7074c73