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A rare case of coexistence of autoimmune polyglandular syndrome type 3 with growth hormone deficiency and hyperthyroidism in a patient with pseudo-Turner’s syndrome
- Source :
- The Journal of International Medical Research, Journal of International Medical Research, Vol 48 (2020)
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Autoimmune polyglandular syndrome (APS) is a rare disease that is characterized by autoimmune reactions to multiple endocrine and non-endocrine organs, which can be divided into four main types. The principal manifestations of APS-3 are autoimmune thyroid disease and other autoimmune diseases, such as type 1 diabetes, atrophic gastritis, pernicious anemia, vitiligo, alopecia, and myasthenia gravis, but not Addison’s disease or hypoparathyroidism. Here we report a case demonstrating the rare coexistence of growth hormone deficiency and hyperthyroidism with sexual dysgenesis, secondary amenorrhea, cardiomegaly, splenomegaly, hypoproteinemia, pleural effusion, seroperitoneum, pericardial effusion, anasarca, osteoporosis, vitamin D deficiency, iron-deficiency anemia, poor blood coagulation, leucocytopenia, peripheral neuropathy, hyperuricemia, ichthyosis, tinea cruris, and onychomycosis.
- Subjects :
- 0301 basic medicine
growth hormone deficiency
medicine.medical_specialty
Medicine (General)
endocrine system diseases
Atrophic gastritis
Anemia
Graves' disease
Turner Syndrome
030209 endocrinology & metabolism
Case Report
Vitiligo
Biochemistry
Anasarca
Hyperthyroidism
amenorrhea
03 medical and health sciences
0302 clinical medicine
R5-920
Addison Disease
medicine
Humans
Polyendocrinopathies, Autoimmune
pernicious anemia
business.industry
Biochemistry (medical)
Cell Biology
General Medicine
medicine.disease
Autoimmune polyglandular syndrome type 3
Dermatology
osteoporosis
030104 developmental biology
Hypoparathyroidism
Growth Hormone
Female
medicine.symptom
business
Graves’ disease
Rare disease
Subjects
Details
- Language :
- English
- ISSN :
- 14732300 and 03000605
- Volume :
- 48
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- The Journal of International Medical Research
- Accession number :
- edsair.doi.dedup.....5711695e0a0a679bacc9c9370a3178b9