Back to Search
Start Over
Calcineurin-Modulated Antimicrobial Peptide Expression Is Required for the Development of Helicoverpa armigera
- Source :
- Frontiers in Physiology, Frontiers in Physiology, Vol 10 (2019)
- Publication Year :
- 2019
- Publisher :
- Frontiers Media S.A., 2019.
-
Abstract
- Helicoverpa armigera is a universal pest around the world that has been extensively used as a model organism for agricultural pests. Calcineurin (CAN) is an important Ca2+-dependent phosphatase that is participated in various biological pathways. Here, we revealed that CAN inhibition significantly arrested H. armigera larval development by reducing larvae weight, prolonging development time and reducing pupate rates. Furthermore, CAN serves as an immune activator and regulates antimicrobial peptide (AMP; cecropin D, attacin, and gloverin) expression by binding with relish transcript factor in H. armigera. This study provides a potential target to control H. armigera by using synergistic agents for pesticides or plant-mediated RNA interference technology.
- Subjects :
- 0106 biological sciences
0301 basic medicine
Physiology
Phosphatase
Biology
Helicoverpa armigera
01 natural sciences
lcsh:Physiology
Biological pathway
03 medical and health sciences
Immune system
RNA interference
Physiology (medical)
calcineurin
Original Research
AMP
lcsh:QP1-981
Activator (genetics)
fungi
food and beverages
IMD pathway
Antimicrobial
biology.organism_classification
Cell biology
relish
Calcineurin
010602 entomology
030104 developmental biology
Subjects
Details
- Language :
- English
- ISSN :
- 1664042X
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Frontiers in Physiology
- Accession number :
- edsair.doi.dedup.....5727b5c6a51c2487c344f4bf64a71d92