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The Risk Factors for the Exacerbation of COVID‐19 Disease: A Case–control Study
- Source :
- Journal of Clinical Nursing
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- AIMS AND OBJECTIVES: To investigate the factors associated with the exacerbations of COVID-19. BACKGROUND: At present, COVID-19 is prevalent in the world, seriously endangering the property and life safety of people around the world. Currently, there are many reports on the clinical features, complications and risk factors of death of COVID-19, but there are few reports on the factors associated with the exacerbation of COVID-19. DESIGN: Case-control Study. METHODS: Patients with COVID-19 were recruited from four designated hospitals for novel coronavirus pneumonia in Xiangyang City, Hubei Province from January to April 2020. The patients were divided into disease exacerbation group (n = 53) and disease stabilisation group (n = 265) according to the disease progression during hospitalisation. Univariate analysis and multivariate logistic regression were used to identify the factors associated with the exacerbation of COVID-19. The research was reported according to STROBE statement. RESULTS: Univariate analysis showed there were significant differences in gender, age, hypertension, heart disease, kidney disease, white blood cell count, percentage of neutrophil, percentage of lymphocyte, C-reactive protein, lactate dehydrogenase, total protein, albumin, creatinine, calcium ion, rate of erythrocyte sedimentation, cough, expectoration, chest tightness, gastrointestinal discomfort and dyspnoea between the two groups. The variables with p
- Subjects :
- China
medicine.medical_specialty
Heart disease
Exacerbation
Disease
Logistic regression
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Humans
030212 general & internal medicine
General Nursing
Univariate analysis
Creatinine
030504 nursing
business.industry
Case-control study
COVID-19
General Medicine
medicine.disease
Hospitalization
Treatment Outcome
chemistry
Case-Control Studies
Disease Progression
0305 other medical science
business
Kidney disease
Subjects
Details
- Language :
- English
- ISSN :
- 13652702 and 09621067
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Nursing
- Accession number :
- edsair.doi.dedup.....5756788612aae95d3db6d7f3d786ad4e
- Full Text :
- https://doi.org/10.1111/jocn.15601