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A new HLA-A Allele, HLA-A*6824, identified in three unrelated individuals*

Authors :
J Morris
S Davey
Nina Bendukidze
R Goodman
Colin Brown
S. Day
Vaughan Carter
T Key
P.P.J. Dunn
Source :
Tissue Antigens. 65:485-487
Publication Year :
2005
Publisher :
Wiley, 2005.

Abstract

A novel allele, human leukocyte antigen (HLA)-A*6824, has been identified in three unrelated individuals of northwestern European origin in a period of less than 4 months, implying that this allele may be quite common in this population. HLA-A*6824 differs from A*680102 by a single nucleotide change at position 275 in exon 2, which results in a conservative amino acid substitution from lysine to arginine in the peptide-binding groove at codon 68.

Details

ISSN :
13990039 and 00012815
Volume :
65
Database :
OpenAIRE
Journal :
Tissue Antigens
Accession number :
edsair.doi.dedup.....578eae4df9d88a21d6e83392736bf475
Full Text :
https://doi.org/10.1111/j.1399-0039.2005.00399.x