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Pargyline and gamma-butyrolactone enhance tyrosine hydroxylase immunostaining of nigrostriatal axons
Pargyline and gamma-butyrolactone enhance tyrosine hydroxylase immunostaining of nigrostriatal axons
- Source :
- Brain research. 556(2)
- Publication Year :
- 1991
-
Abstract
- Administration of pargyline or gamma-butyrolactone enhanced immunostaining of tyrosine hydroxylase immunoreactive axons in the striatum. The qualitative characteristics of the enhancement were compound dependent and the enhancement was not associated with an increase in the amount of tyrosine hydroxylase within the striatum. These results demonstrate the pharmacological enhancement of immunostaining for neurotransmitter synthetic enzymes in the absence of increased synthesis.
- Subjects :
- medicine.medical_specialty
Tyrosine 3-Monooxygenase
Nigrostriatal pathway
Striatum
Biology
chemistry.chemical_compound
Mice
4-Butyrolactone
Internal medicine
Basal ganglia
medicine
Animals
Neurotransmitter
Molecular Biology
Tyrosine hydroxylase
Staining and Labeling
General Neuroscience
Pargyline
Immunohistochemistry
Axons
Corpus Striatum
Mice, Inbred C57BL
Substantia Nigra
medicine.anatomical_structure
Endocrinology
nervous system
chemistry
Female
Neurology (clinical)
Immunostaining
Developmental Biology
medicine.drug
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 556
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Brain research
- Accession number :
- edsair.doi.dedup.....57a97298dfa80d0352100384514c27c4