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Aging does not alter muscarinic receptor-mediated inhibition of cyclic AMP formation in the striatum and hippocampus
- Source :
- Brain Research. 534:234-236
- Publication Year :
- 1990
- Publisher :
- Elsevier BV, 1990.
-
Abstract
- The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats.
- Subjects :
- Male
Agonist
Aging
medicine.medical_specialty
medicine.drug_class
Hippocampus
Striatum
Biology
chemistry.chemical_compound
Internal medicine
Muscarinic acetylcholine receptor
Cyclic AMP
Muscarinic acetylcholine receptor M4
medicine
Animals
Cyclic adenosine monophosphate
Molecular Biology
Acetylcholine receptor
Forskolin
General Neuroscience
Receptors, Muscarinic
Corpus Striatum
Rats, Inbred F344
Rats
Endocrinology
chemistry
Organ Specificity
Carbachol
Neurology (clinical)
Developmental Biology
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 534
- Database :
- OpenAIRE
- Journal :
- Brain Research
- Accession number :
- edsair.doi.dedup.....580ee0b736e6aa976f19cd8aec25a5d3