Ten years of the Russian metabolomics: history of development and achievements

Metabolomics is one of the omics sciences, the technologies of which are widely used today in many life sciences. Its application influenced the discovery of new biomarkers of diseases, the description of biochemical processes occurring in many organisms, laid the basis for a new generation of clinical laboratory diagnostics. The purpose of this review is to show how metabolomics is represented in the studies of Russian scientists, to demonstrate the main directions and achievements of the Russian science in this field. The review also highlights the history of metabolomics, existing problems and the place of Russian metabolomics in their solution.Metabolomika — odna iz omiksnykh nauk, tekhnologii kotoroĭ shiroko ispol'zuiutsia segodnia vo mnogikh naukakh o zhizni. Ee primenenie dalo impul's dlia otkrytiia novykh biomarkerov zabolevaniĭ, opisaniia biokhimicheskikh protsessov, protekaiushchikh vo mnogikh organizmakh, zalozhilo osnovy dlia klinicheskoĭ laboratornoĭ diagnostiki novogo pokoleniia. Tsel'iu dannogo obzora bylo pokazat', naskol'ko metabolomika predstavlena v issledovaniiakh rossiĭskikh uchenykh, kakie osnovnye napravleniia issledovaniĭ byli imi vybrany, prodemonstrirovat' uspekhi i zaslugi otechestvennoĭ nauki v dannoĭ oblasti. V obzore takzhe rassmotrena istoriia vozniknoveniia metabolomiki, osnovnye ee napravleniia, sushchestvuiushchie problemy i mesto rossiĭskoĭ metabolomiki v ikh reshenii.