Supplementary Figures from Targeting FSTL1 Prevents Tumor Bone Metastasis and Consequent Immune Dysfunction

PDF file, 1193K, Figure S1. Snail+ tumor cells frequently metastasize into bone marrow. Figure S2. Differentiation activity of the specific subpopulations isolated from the Snail+ tumor-stimulated BMCs. Figure S3. The Snail+ tumor-induced MSCs promote tumor metastatic seeding into bone. Figure S4. Increase of fstl1 and its receptor dip2a mRNA expressions in Snail+ tumor cells. Figure S5. FSTL1-knockdown suppresses metastatic seeding of human tumor cells into bone. Figure S6. FSTL1-induced cancer bone metastasis mechanism.