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Lewy body constipation
- Source :
- Journal of the Anus, Rectum and Colon, Journal of the Anus, Rectum and Colon, Vol 3, Iss 1, Pp 10-17 (2019)
- Publication Year :
- 2019
- Publisher :
- The Japan Society of Coloproctology, 2019.
-
Abstract
- We systematically reviewed literature regarding "Lewy body constipation", i.e., constipation due to Lewy body diseases (LBD), with minimal neurologic symptoms. Epidemiology and pathology studies showed that LBD can start with constipation alone, mostly due to neuronal loss and appearance of Lewy bodies in the myenteric plexus. Because LBD significantly increases with age, "Lewy body constipation" may also increase with age. Neuroimaging methods such as metaiodobenzylguanidine (MIBG) scintigraphy and dopamine transporter (DAT) scan provide a way to detect "Lewy body constipation." Key for "Lewy body constipation" includes minimal non-motor features such as REM sleep behavior disorder (night talking). Add-on therapy may be required to ameliorate constipation in patients. Diagnosis is not always easy; therefore, collaboration of gastroenterologists and neurologists is highly recommended to maximize patients' quality of life. In conclusion, "Lewy body constipation" might become a distinct category among geriatric constipation, regarding patients' follow-up and their management.
- Subjects :
- medicine.medical_specialty
Pediatrics
neuroimaging
Constipation
Parkinson's disease
Lewy body
Dementia with Lewy bodies
business.industry
Review Article
constipation
medicine.disease
REM sleep behavior disorder
Lewy body constipation
Quality of life
Neuroimaging
Epidemiology
medicine
lcsh:Diseases of the digestive system. Gastroenterology
lcsh:RC799-869
medicine.symptom
dementia with Lewy bodies
business
Subjects
Details
- ISSN :
- 24323853
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of the Anus, Rectum and Colon
- Accession number :
- edsair.doi.dedup.....58678d2bc68e7203aa55c003d261f3c0