Back to Search
Start Over
Evidence for Multiple Retroposition Events and Gene Evolution in the ADP/ATP Translocase Gene Family in Ranid Frogs
- Source :
- Journal of Heredity. 98:300-310
- Publication Year :
- 2007
- Publisher :
- Oxford University Press (OUP), 2007.
-
Abstract
- Analysis of partial ADP/ATP Translocase gene (Aat) sequences from 11 species of Ranid frogs (Amphibia: Ranidae) identified multiple Aat gene copies. All frog species examined had at least one of the 2 Aat gene copies differing mainly by presence or absence of an approximately 85-bp intron sequence. The sequence data suggest that the gene variant with intron is the ancestral Aat form, whereas the other variants are retroposed copies. Surprisingly, a phylogenetic analysis suggests that multiple reptroposition events have taken place in the Ranid frogs. An analysis including sequences from Drosophila, zebra fish, Xenopus, mouse, and human indicated that all the frog Aat sequences form a monophyletic group with mammalian X-chromosomal Ant2 as a sister unit. Furthermore, the selection test suggested that different variants of the Aat gene appear to have evolved under different modes of evolution (viz., neutral, purifying, and positive selection), and the evolutionary history of different AAT variants appears to differ even among different species.
- Subjects :
- 0106 biological sciences
congenital, hereditary, and neonatal diseases and abnormalities
Ranidae
Retroelements
Genetic Speciation
Xenopus
Biology
010603 evolutionary biology
01 natural sciences
Evolution, Molecular
03 medical and health sciences
Monophyly
Genetics
Animals
Gene family
Selection, Genetic
Molecular Biology
Gene
Phylogeny
Genetics (clinical)
030304 developmental biology
Sequence (medicine)
0303 health sciences
Phylogenetic tree
Intron
Genetic Variation
biology.organism_classification
Haplotypes
Multigene Family
ATP–ADP translocase
Mitochondrial ADP, ATP Translocases
Biotechnology
Subjects
Details
- ISSN :
- 14657333 and 00221503
- Volume :
- 98
- Database :
- OpenAIRE
- Journal :
- Journal of Heredity
- Accession number :
- edsair.doi.dedup.....58738139d62c30f1b348fa4580e3d463