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Author Correction: Improved reference genome of the arboviral vector Aedes albopictus
- Source :
- Genome Biology, Genome Biology, BioMed Central, 2021, 22 (1), pp.205. ⟨10.1186/s13059-021-02431-x⟩, Genome Biology, Vol 22, Iss 1, Pp 1-1 (2021), Genome Biology, 2021, 22 (1), pp.205. ⟨10.1186/s13059-021-02431-x⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- The Asian tiger mosquito Aedes albopictus is globally expanding and has become the main vector for human arboviruses in Europe. With limited antiviral drugs and vaccines available, vector control is the primary approach to prevent mosquito-borne diseases. A reliable and accurate DNA sequence of the Ae. albopictus genome is essential to develop new approaches that involve genetic manipulation of mosquitoes.We use long-read sequencing methods and modern scaffolding techniques (PacBio, 10X, and Hi-C) to produce AalbF2, a dramatically improved assembly of the Ae. albopictus genome. AalbF2 reveals widespread viral insertions, novel microRNAs and piRNA clusters, the sex-determining locus, and new immunity genes, and enables genome-wide studies of geographically diverse Ae. albopictus populations and analyses of the developmental and stage-dependent network of expression data. Additionally, we build the first physical map for this species with 75% of the assembled genome anchored to the chromosomes.The AalbF2 genome assembly represents the most up-to-date collective knowledge of the Ae. albopictus genome. These resources represent a foundation to improve understanding of the adaptation potential and the epidemiological relevance of this species and foster the development of innovative control measures.
- Subjects :
- Aedes albopictus
QH301-705.5
[SDV]Life Sciences [q-bio]
Computational biology
Mosquito Vectors
Biology
QH426-470
Chromosomes
03 medical and health sciences
0302 clinical medicine
Genome Size
Aedes
Genetics
Animals
RNA, Small Interfering
Biology (General)
Author Correction
ComputingMilieux_MISCELLANEOUS
030304 developmental biology
0303 health sciences
Genome
Immunity
Chromosome Mapping
biology.organism_classification
Human genetics
3. Good health
Insect Vectors
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
Vector (epidemiology)
[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology
Transcriptome
030217 neurology & neurosurgery
Arboviruses
Reference genome
Subjects
Details
- Language :
- English
- ISSN :
- 14656906 and 1474760X
- Database :
- OpenAIRE
- Journal :
- Genome Biology, Genome Biology, BioMed Central, 2021, 22 (1), pp.205. ⟨10.1186/s13059-021-02431-x⟩, Genome Biology, Vol 22, Iss 1, Pp 1-1 (2021), Genome Biology, 2021, 22 (1), pp.205. ⟨10.1186/s13059-021-02431-x⟩
- Accession number :
- edsair.doi.dedup.....58dd8047dcc4813ea81d1303af16b1bc