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Supplementary Tables from Ponatinib Inhibits Polyclonal Drug-Resistant KIT Oncoproteins and Shows Therapeutic Potential in Heavily Pretreated Gastrointestinal Stromal Tumor (GIST) Patients

Authors :
Victor M. Rivera
Sebastian Bauer
Jonathan A. Fletcher
Michael C. Heinrich
Tim Clackson
Frank Wang
Anna Kohlmann
Youngchul Song
Yaoyu Ning
Scott Wardwell
Julia Ketzer
Meijun Zhu
Grant Eilers
Cesar Serrano
Tianjun Zhou
Alexa Schrock
Sadanand Vodala
Rana Anjum
Joseph M. Gozgit
Andrew P. Garner
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Tables. Table S1. In Vitro Kinase IC50 Values (nM) for Native and Mutant Recombinant KIT. Table S2. Summary of Ba/F3 KIT Cell Lines Generated in this Study. Table S3. Summary of IC50 Viability Values in Ba/F3 KIT Cells. Table S4. Summary of KIT Driven Ba/F3 In Vivo Studies.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....595ad2d3921b32e51857d8df11c4a7ca
Full Text :
https://doi.org/10.1158/1078-0432.22457165