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Comparing the Tolerability of a Novel Wound Closure Device Using a Porcine Wound Model
- Source :
- Advances in Wound Care. 7:177-184
- Publication Year :
- 2018
- Publisher :
- Mary Ann Liebert Inc, 2018.
-
Abstract
- Objective: To compare the tolerability and mechanical tensile strength of acute skin wounds closed with nylon suture plus a novel suture bridge device (SBD) with acute skin wounds closed with nylon suture in a porcine model. Approach: Four Yucatan pigs each received 12 4.5 cm full-thickness incisions that were closed with 1 of 4 options: Suture bridge with nylon, suture bridge with nylon and subdermal polyglactin, nylon simple interrupted, and nylon simple interrupted with subdermal polyglactin. Epithelial reaction, inflammation, and scarring were examined histologically at days 10 and 42. Wound strength was examined mechanically at days 10 and 42 on ex vivo wounds from euthanized pigs. Results: Histopathology in the suture entry/exit planes showed greater dermal inflammation with a simple interrupted nylon suture retained for 42 days compared with the SBD retained for 42 days (p
- Subjects :
- Suture bridge
medicine.medical_specialty
Wound strength
integumentary system
Skin wound
business.industry
technology, industry, and agriculture
hemic and immune systems
chemical and pharmacologic phenomena
Surgical wound
Critical Care and Intensive Care Medicine
Technology Advances
Surgery
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Tolerability
Suture (anatomy)
030220 oncology & carcinogenesis
Ultimate tensile strength
Emergency Medicine
medicine
Wound closure
business
Subjects
Details
- ISSN :
- 21621934 and 21621918
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Advances in Wound Care
- Accession number :
- edsair.doi.dedup.....596efee1791319fe20a58f2fe89f75cf