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Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia
- Source :
- Journal of Neonatal Nursing, 24(6), 313-317. Elsevier BV, the PharmaCool studygroup 2018, ' Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia ', Journal of Neonatal Nursing, vol. 24, no. 6, pp. 313-317 . https://doi.org/10.1016/j.jnn.2018.07.004, Journal of Perinatal & Neonatal Nursing, 24, 313-317. Lippincott Williams & Wilkins
- Publication Year :
- 2018
-
Abstract
- The therapeutic effect of moderate hypothermia in infants with HIE after perinatal asphyxia can be counteracted by stress which should therefore be minimized. Objective: of study was to gain insight in the COMFORTNeo-scale to measure stress during therapeutic hypothermia. Stress was measured prospectively by means of the COMFORTNeo-scale (CNS), twice a day, during hypothermia-, rewarming- and stabilization phase in a cohort of 133 neonates with perinatal asphyxia who participated in the PharmaCool study. A total of 994 CNS scores were collected; median score CNS 9 (IQR 7–11). Despite analgesic, sedative and anticonvulsant drugs 10% of the scores indicated moderate to severe stress during treatment. The use of these drugs as well as mechanical ventilation interfered with CNS score (respectively odds ratio 0.74 and 0.61) Interference of aEEG, hypothermia phase and gender were not confirmed. The COMFORTNeo-scale can, with the necessary caution, be used for the assessment of stress during therapeutic hypothermia treatment. Other options should be explored.
- Subjects :
- Mechanical ventilation
business.industry
medicine.drug_class
medicine.medical_treatment
Analgesic
Therapeutic effect
Odds ratio
Hypothermia
medicine.disease
Pediatrics
Perinatal asphyxia
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
Anesthesia
Sedative
Cohort
Medicine
medicine.symptom
business
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 13551841 and 08932190
- Database :
- OpenAIRE
- Journal :
- Journal of Neonatal Nursing, 24(6), 313-317. Elsevier BV, the PharmaCool studygroup 2018, ' Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia ', Journal of Neonatal Nursing, vol. 24, no. 6, pp. 313-317 . https://doi.org/10.1016/j.jnn.2018.07.004, Journal of Perinatal & Neonatal Nursing, 24, 313-317. Lippincott Williams & Wilkins
- Accession number :
- edsair.doi.dedup.....5acd09ab76ebadddd241d8c712e090df