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Human seminal fibrinolytic activity: specific determinations of tissue plasminogen activator and urokinase
- Source :
- Andrologia. 23(1)
- Publication Year :
- 1991
-
Abstract
- Summary. The determination of total fibrinolytic activity of ejaculates was realized by fibrin plate method. For the same seminal samples, tissue plasminogen activator (t-PA), urinary plasminogen activator (uPA) antigens and uPA activity were specifically quantified. The seminal values were fifty times higher than in the blood for t-PA and fifteen times for uPA. There was no correlation between the both levels but from split ejaculates measurements a higher concentration was observed in all first fractions. By zymography assays, it was shown that seminal plasminogen activators are under active forms. The lack of proUrokinase in semen was also demonstrated.
- Subjects :
- Adult
Male
medicine.medical_specialty
Urology
Urinary system
Semen
Biology
Tissue plasminogen activator
Plasminogen Activators
Endocrinology
Antigen
Internal medicine
medicine
Humans
Zymography
Urokinase
chemistry.chemical_classification
Fibrinolysis
General Medicine
Urokinase-Type Plasminogen Activator
Enzyme
chemistry
Tissue Plasminogen Activator
Plasminogen activator
medicine.drug
Subjects
Details
- ISSN :
- 03034569
- Volume :
- 23
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Andrologia
- Accession number :
- edsair.doi.dedup.....5ad8dd65087f84b0da59c89d7ee65019