ZIKV replication is differential in explants and cells of human placental which is suppressed by HSV-2 coinfection

Authors :: Lauana Ribas Torres
Lyana Rodrigues Pinto Lima Capobianco
Audrien Alves Andrade de Souza
Camilla Rodrigues de Almeida Ribeiro
Cynthia Cascabulho
Luciana Ribeiro Garzoni
Elyzabeth Avvad Portari
Marcelo Aranha Gardel
Marcelo Meuser-Batista
Vanessa Salete de Paula
Elen Mello de Souza
Source :: Virology. 570
Publication Year :: 2021
Abstract: During the Zika fever outbreak in Brazil in 2015-2016, only some babies from infected mothers had teratogenic effects, suggesting that cofactors may influence congenital transmission. We investigated the ZIKV infection profile in explants and isolated cells from full-term human placenta to infection with the Brazilian Zika virus strain (ZIKV

Subjects :: Coinfection
Pregnancy
Zika Virus Infection
Virology
Herpesvirus 2, Human
Placenta
Humans
Female
Zika Virus

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