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Diffusion tensor imaging of the normal prostate at 3 Tesla
Diffusion tensor imaging of the normal prostate at 3 Tesla
- Source :
- European radiology. 18(4)
- Publication Year :
- 2007
-
Abstract
- The aim of this study was to assess the feasibility of diffusion tensor imaging (DTI) of the prostate and to determine normative fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of healthy prostate with a 3-Tesla magnetic resonance imaging (MRI) system. Thirty volunteers with a mean age of 28 (25-35) years were scanned with a 3-Tesla MRI (Intera Achieva; Philips, The Netherlands) system using a six-channel phased array coil. Initially, T2-weighted turbo spin-echo (TSE) axial images of the prostate were obtained. In two subjects, a millimetric hypointense signal change was detected in the peripheral zones on T2-weighted TSE images. These two subjects were excluded from the study. DTI with single-shot echo-planar imaging (ssEPI) was performed in the remaining 28 subjects. ADC and FA values were measured using the manufacturer supplied software by positioning 9-pixel ROIs on each zone. Differences between parameters of the central and peripheral zones were assessed. Mean ADC value of the central (1.220 +/- 0.271 x 10(-3) mm(2)/s) was found to be significantly lower when compared with the peripheral gland (1.610 +/- 0.347 x 10(-3) mm(2)/s) (P0.01). Mean FA of the central gland was significantly higher (0.26), compared with the peripheral gland (0.16) (P0.01). This study shows the feasibility of prostate DTI with a 3-Tesla MR system and the normative FA and ADC values of peripheral and central zones of the normal prostate. The results are compatible with the microstructural organization of the gland.
- Subjects :
- Adult
Male
medicine.medical_specialty
Prostate
Fractional anisotropy
Image Processing, Computer-Assisted
Medicine
Effective diffusion coefficient
Humans
Radiology, Nuclear Medicine and imaging
Prospective Studies
Neuroradiology
medicine.diagnostic_test
business.industry
Ultrasound
Magnetic resonance imaging
General Medicine
Peripheral
medicine.anatomical_structure
Diffusion Magnetic Resonance Imaging
Radiology
business
Nuclear medicine
Algorithms
Diffusion MRI
Subjects
Details
- ISSN :
- 09387994
- Volume :
- 18
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- European radiology
- Accession number :
- edsair.doi.dedup.....5afd7abda2dddb992fc8f254c65081c7