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Additional file 1: of Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations

Authors :
Cartier, Jessy
Smith, Thomas
Thomson, John
Rose, Catherine
Batbayar Khulan
Heger, Andreas
Meehan, Richard
Drake, Amanda
Publication Year :
2018
Publisher :
figshare, 2018.

Abstract

Supplementary methods. ERRBS on germ cells. Figure S1. 5mC profiling in sperm. Figure S2. DNA methylation in the developing germline is unaffected by Dex treatment across the genome. Figure S3. DNA methylation in the developing germline is unaffected by Dex treatment: reproducibility and power calculations. Figure S4. sRNA-Seq analysis is sufficiently powered to detect differential expression. Figure S5. F1-sperm sRNA expression shows consistent lack of affect for Dex treatment for two quantification methods. Figure S6. Fold changes between Dex and Veh sRNA expression and histone methylation and are not correlated. (PDF 1566 kb)

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....5b495a90c4dadfdd6b0f107cac1bb019
Full Text :
https://doi.org/10.6084/m9.figshare.6126137.v1