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Prognostic significance of the combination of preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in patients with renal cell carcinoma after nephrectomy
- Source :
- BMC Urology, Vol 18, Iss 1, Pp 1-8 (2018), BMC Urology
- Publication Year :
- 2018
- Publisher :
- BMC, 2018.
-
Abstract
- Background To evaluate the prognostic significance of the novel index combining preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in renal cell carcinoma (RCC) patients. Methods We enrolled 1360 patients who underwent nephrectomy in our institution from 2001 to 2010. The cutoff values for HALP, neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio were defined by using X-tile software. Survival was analyzed by the Kaplan–Meier method, with differences analyzed by the log-rank test. Multivariate Cox proportional-hazards model was used to evaluate the prognostic significance of HALP for RCC. Results Low HALP was significantly associated with worse clinicopathologic features. Kaplan-Meier and log-rank tests revealed that HALP was strongly correlated with cancer specific survival (P
- Subjects :
- Blood Platelets
Male
0301 basic medicine
medicine.medical_specialty
Multivariate analysis
Urology
Lymphocyte
medicine.medical_treatment
lcsh:RC870-923
Gastroenterology
Nephrectomy
Hemoglobins
03 medical and health sciences
0302 clinical medicine
Renal cell carcinoma
Internal medicine
Preoperative Care
Humans
Medicine
Platelet
Lymphocytes
Stage (cooking)
Carcinoma, Renal Cell
Serum Albumin
Aged
Retrospective Studies
Platelet Count
business.industry
Albumin
General Medicine
Middle Aged
Nomogram
medicine.disease
Prognosis
lcsh:Diseases of the genitourinary system. Urology
Kidney Neoplasms
030104 developmental biology
medicine.anatomical_structure
Reproductive Medicine
030220 oncology & carcinogenesis
HALP
Female
business
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 14712490
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Urology
- Accession number :
- edsair.doi.dedup.....5bd9aa62704e457d32d7ec9153f19822