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Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with stargardt disease

Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with stargardt disease

Authors :
Gerald A. Fishman
Mohamed A. Genead
Anastasios Anastasakis
Source :
British Journal of Ophthalmology. 95:689-693
Publication Year :
2010
Publisher :
BMJ, 2010.

Abstract

Aims To evaluate the presence of peripapillary retinal nerve fibre layer (RNFL) defects in patients with Stargardt disease by using spectral-domain optical coherence tomography (SD-OCT). Methods Fifty-two eyes of 27 patients with Stargardt disease underwent peripapillary RNFL thickness measurements using SD-OCT. Results Twenty-seven patients with Stargardt disease were enrolled. Their mean (±SD) age was 38.3 (14.7) years. Fourteen patients (51.9%) showed a thinning of the peripapillary RNFL in one or more quadrants in at least one eye, and four patients (14.8%) in both eyes. Five patients (18.5%) showed a thickening of the peripapillary RNFL in at least one eye, and four patients (14.8%) in both eyes. Conclusion This study demonstrated the presence of defects in the peripapillary RNFL thickness in patients with Stargardt disease by using SD-OCT. It would be clinically prudent that Stargardt patients considered for various treatment options be considered for RNFL thickness measurements.

Details

ISSN :
00071161
Volume :
95
Database :
OpenAIRE
Journal :
British Journal of Ophthalmology
Accession number :
edsair.doi.dedup.....5c1a024b4ed9e0c4329f09750d537323
Full Text :
https://doi.org/10.1136/bjo.2010.189720