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Ideal cardiovascular health metrics and the risk of non‐alcoholic fatty liver disease: A cross‐sectional study in northern China

Authors :
Xueyu Chen
Long Ji
Youxin Wang
Yanru Chen
Huamin Liu
Xia Feng
Xuezhen Liu
Yan Yao
Shasha Guo
Yong Zhou
Dong Li
Zhongni Liu
Likun Ma
Source :
Liver International. 39:950-955
Publication Year :
2019
Publisher :
Wiley, 2019.

Abstract

BACKGROUND AND PURPOSE The components of ideal cardiovascular health (CVH) metrics have been shown to be associated with non-alcoholic fatty liver disease (NAFLD). The present study aimed to determine the association between ideal CVH metrics and NAFLD. METHODS A total of 10,511 participants (47.26% men) aged 18 to 92 years were selected from the Jidong and Kailuan communities. Ideal CVH was based on 7 ideal CVH metrics: smoking, body mass index (BMI), physical activity, diet, total cholesterol, blood pressure and fasting blood glucose. NAFLD was determined by abdominal ultrasonography. All participants underwent questionnaire assessments and clinical and laboratory examinations. Logistic regression models were used to analyse the relationship of CVH metrics and the number of ideal CVH metrics with NAFLD. RESULTS The prevalence rates of NAFLD by CVH summary score quartiles were 64.38% (2,015/3,130), 50.16% (786/1,567), 33.28% (1,194/3,588) and 20.89% (465/2,226). Participants in the highest quartile showed a lower odds ratio (OR) than those in the lowest quartile (fully adjusted OR: 0.17, 95% CI: 0.17-0.20, P

Details

ISSN :
14783231 and 14783223
Volume :
39
Database :
OpenAIRE
Journal :
Liver International
Accession number :
edsair.doi.dedup.....5ccd9955dbbaf084bb549583ac3ccf07