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Effects of Lens-Care Solutions on Hydrogel Lens Performance
- Source :
- Kitamata-Wong, B; Yuen, T; Li, W; Svitova, T; Zhou, Y; & Lin, MC. (2017). Effects of Lens-Care Solutions on Hydrogel Lens Performance. Optometry and Vision Science, 94(11), 1036-1046. doi: 10.1097/OPX.0000000000001125. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/7cn310kf, Optometry and vision science : official publication of the American Academy of Optometry, vol 94, iss 11
- Publication Year :
- 2017
- Publisher :
- eScholarship, University of California, 2017.
-
Abstract
- Author(s): Kitamata-Wong, Britney; Yuen, Tiffany; Li, Wing; Svitova, Tatyana; Zhou, Yixiu; Lin, Meng C | Abstract: SignificanceLens care multipurpose solutions (MPSs) can have varying effects on contact lens (CL) surface properties and the corneal epithelium.PurposeThe aim of this study was to investigate the short-term effects of newer MPS on CL comfort and dryness, prelens tear-film stability, and ocular-surface health. In vitro study was also performed to assess the effect of MPSs on CL surface properties.MethodsAcuvue 2 CLs were soaked in control solution, Clear Care (CC), or test solutions: PureMoist, Biotrue, RevitaLens (RL), or saline solution (SS). Over four visits, subjects were exposed to control solution in one eye and to test solution in the contralateral eye for 2 hours using presoaked CLs. Contact lens comfort and dryness, ocular-surface health assessment, prelens noninvasive tear breakup time, and corneal epithelial permeability measured with fluorometry were assessed. Captive-sessile bubble technique evaluated CL wettability and viscous drag in vitro.ResultsAt 10 minutes, mean comfort ± SD with PureMoist (76 ± 22) was lower than CC (86 ± 15, P = .02), Biotrue (92 ± 9, P l .005), RL (90 ± 13, P l .005), and SS (90 ± 14, P l .005). No other difference in comfort or dryness was noted. RevitaLens was associated with greater corneal epithelial permeability than CC (P = .020) and increased corneal staining compared with all MPSs (P l .005 for all). RevitaLens was also associated with longer prelens noninvasive tear breakup than CC (P l .005). In vitro results agreed with clinical findings of tear-film stability as RL reduced viscous drag. Contact lens surface wettability was enhanced by all MPSs in comparison to SS.ConclusionsDifferences of MPSs on the ocular surface were found in vivo and in vitro. RL caused the greatest corneal epithelium disruption but also associated with higher tear-film stability. The effect of MPSs on CL surface properties in vitro seems to reflect how MPSs altered prelens tear stability.
- Subjects :
- Adult
Male
medicine.medical_specialty
Hydrophilic
Adolescent
Contact Lenses
Surface Properties
medicine.medical_treatment
Dry Eye Syndromes
Ophthalmology & Optometry
Medical and Health Sciences
Cornea
03 medical and health sciences
Young Adult
0302 clinical medicine
Double-Blind Method
In vivo
Ophthalmology
medicine
Humans
Saline
Corneal epithelium
Cross-Over Studies
Chemistry
Contact Lenses, Hydrophilic
eye diseases
Contact lens
medicine.anatomical_structure
Lens (anatomy)
030221 ophthalmology & optometry
Wettability
Female
Contact Lens Solutions
sense organs
030217 neurology & neurosurgery
Optometry
Test solution
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Kitamata-Wong, B; Yuen, T; Li, W; Svitova, T; Zhou, Y; & Lin, MC. (2017). Effects of Lens-Care Solutions on Hydrogel Lens Performance. Optometry and Vision Science, 94(11), 1036-1046. doi: 10.1097/OPX.0000000000001125. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/7cn310kf, Optometry and vision science : official publication of the American Academy of Optometry, vol 94, iss 11
- Accession number :
- edsair.doi.dedup.....5cd209ea3040c2233b8e0d3e3a431538