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Ypsiyunnosides A-E, Five New Cholestanol Glycosides from Ypsilandra yunnanensis
- Source :
- Natural Products and Bioprospecting
- Publication Year :
- 2016
-
Abstract
- Phytochemical investigation on the whole plants of Ypsilandra yunnanensis was carried out for the first time and led to the isolation of five new cholestanol glycosides, ypsiyunnosides A–E (1–5), and one known analogue. Their structures were determined mainly by detailed spectroscopic analysis, including extensive 1D and 2D NMR, MS and UV, as well as chemical methods. Among them, compound 1 possessed a rare 6/6/6/5/5 fused-rings cholestanol sketelon, which was identified as (23R,25R)-3β,16α,26-triol-16,23-cyclocholest-5,17(20)-dien-22-one. Their induced platelet aggregation activities and cytotoxicities were evaluated. Graphical Abstract Five new cholestanol glycosides, ypsiyunnosides A–E (1–5), were isolated from the whole plants of Ypsilandra yunnanensis. Compound 1 possessed a rare 6/6/6/5/5 fused-rings cholestanol sketelon. Their structures were elucidated by a combination of 1D and 2D NMR, MS and chemical analysis. Electronic supplementary material The online version of this article (doi:10.1007/s13659-016-0098-2) contains supplementary material, which is available to authorized users.
- Subjects :
- Stereochemistry
Plant Science
Toxicology
01 natural sciences
Biochemistry
Analytical Chemistry
Induced platelet aggregation
Botany
Liliaceae
Pharmacology
chemistry.chemical_classification
Cholestane glycoside
biology
010405 organic chemistry
Chemistry
Cholestanol
Organic Chemistry
Glycoside
Ypsiyunnosides A–E
biology.organism_classification
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Phytochemical
Plant biochemistry
Ypsilandra yunnanensis
Original Article
Two-dimensional nuclear magnetic resonance spectroscopy
Food Science
Subjects
Details
- ISSN :
- 21922195
- Volume :
- 6
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Natural products and bioprospecting
- Accession number :
- edsair.doi.dedup.....5cf8a301bdcd70a789734161fd103a76