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Chromosomal aberrations induced by restriction endonucleases

Authors :
G. Obea
Caterina Tanzarella
Francesca Degrassi
R. De Salvia
G. Palitti
Source :
Mutation research. 150(1-2)
Publication Year :
1985

Abstract

Restriction endonucleases (REs) are able to induce chromosomal aberrations in Chinese hamster ovary (CHO) cells. The G1 phase of the cell cycle seems to be especially sensitive for the induction of chromosomal aberrations by REs. The different capacities of REs to induce chromosomal aberrations are probably correlated with the number of recognition sites in the genome.

Details

ISSN :
00275107
Volume :
150
Issue :
1-2
Database :
OpenAIRE
Journal :
Mutation research
Accession number :
edsair.doi.dedup.....5e04aa438a0bd9379f155d8477b91470