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ArrayExpress update—from an archive of functional genomics experiments to the atlas of gene expression

Authors :
Tomasz Adamusiak
Anjan Sharma
Faisal I. Rezwan
Sudeshna Guha Neogi
Pavel Kurnosov
Susanna-Assunta Sansone
Xiangqun Zheng Bradley
Nataliya Sklyar
Ekaterina Pilicheva
Tim F. Rayner
Richard M.R. Coulson
Gabriella Rustici
Miroslaw Dylag
Ugis Sarkans
Eamonn Maguire
Ibrahim Emam
Mohammadreza Shojatalab
Marco Brandizi
Hugo Bérubé
James Malone
Philippe Rocca-Serra
Margus Lukk
Helen Parkinson
Roby Mani
Ele Holloway
Misha Kapushesky
Anna Farne
Eleanor Williams
Niran Abeygunawardena
Nikolay Kolesnikov
Tony Burdett
Mengyao Zhao
Alvis Brazma
Maria Krestyaninova
Source :
Nucleic Acids Research
Publication Year :
2008
Publisher :
Oxford University Press, 2008.

Abstract

ArrayExpress http://www.ebi.ac.uk/arrayexpress consists of three components: the ArrayExpress Repository--a public archive of functional genomics experiments and supporting data, the ArrayExpress Warehouse--a database of gene expression profiles and other bio-measurements and the ArrayExpress Atlas--a new summary database and meta-analytical tool of ranked gene expression across multiple experiments and different biological conditions. The Repository contains data from over 6000 experiments comprising approximately 200,000 assays, and the database doubles in size every 15 months. The majority of the data are array based, but other data types are included, most recently-ultra high-throughput sequencing transcriptomics and epigenetic data. The Warehouse and Atlas allow users to query for differentially expressed genes by gene names and properties, experimental conditions and sample properties, or a combination of both. In this update, we describe the ArrayExpress developments over the last two years.

Details

Language :
English
ISSN :
13624962 and 03051048
Volume :
37
Database :
OpenAIRE
Journal :
Nucleic Acids Research
Accession number :
edsair.doi.dedup.....5e07b01053767aed8e315532e69d299e