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An admixture analysis of age of onset in agoraphobia
- Source :
- Journal of Affective Disorders, 180, 112-115. Elsevier, Journal of Affective Disorders, 180, 112-115, Tibi, L, van Oppen, P C, Aderka, I M, van Balkom, A J L M, Batelaan, N M, Spinhoven, P, Penninx, B W J H & Anholt, G E 2015, ' An admixture analysis of age of onset in agoraphobia ', Journal of Affective Disorders, vol. 180, pp. 112-115 . https://doi.org/10.1016/j.jad.2015.03.064
- Publication Year :
- 2015
-
Abstract
- Background Age of onset is an important epidemiological indicator in characterizing disorders׳ subtypes according to demographic, clinical and psychosocial determinants. While investigated in various psychiatric conditions, age of onset and related characteristics in agoraphobia have yet to be examined. In light of the new diagnostic status in the DSM-5 edition of agoraphobia as independent from panic disorder, research on agoraphobia as a stand-alone disorder is needed. Methods Admixture analysis was used to determine the best-fitting model for the observed ages at onset of 507 agoraphobia patients participating in the Netherlands Study of Depression and Anxiety (age range 18–65). Associations between agoraphobia age of onset and different demographic, clinical and psychosocial determinants were examined using multivariate logistic regression analysis. Results Admixture analyses identified two distributions of age of onset, with 27 as the cutoff age (≤27; early onset, >27; late onset). Early onset agoraphobia was only independently associated with family history of anxiety disorders (p Limitations Age of onset was assessed retrospectively, and analyses were based on cross-sectional data. Conclusion The best distinguishing age of onset cutoff of agoraphobia was found to be 27. Early onset agoraphobia might constitute of a familial subtype. As opposed to other psychiatric disorders, early onset in agoraphobia does not indicate for increased clinical severity and/or disability.
- Subjects :
- Adult
Male
Age of onset
Late onset
behavioral disciplines and activities
Young Adult
SDG 3 - Good Health and Well-being
mental disorders
medicine
Humans
Risk factor
Family history
Agoraphobia
Aged
Netherlands
Family Health
Models, Statistical
Panic disorder
Middle Aged
medicine.disease
Anxiety Disorders
humanities
Psychiatry and Mental health
Clinical Psychology
Cross-Sectional Studies
Anxiety
Female
medicine.symptom
Psychology
Psychosocial
Clinical psychology
Subjects
Details
- Language :
- English
- ISSN :
- 01650327
- Database :
- OpenAIRE
- Journal :
- Journal of Affective Disorders, 180, 112-115. Elsevier, Journal of Affective Disorders, 180, 112-115, Tibi, L, van Oppen, P C, Aderka, I M, van Balkom, A J L M, Batelaan, N M, Spinhoven, P, Penninx, B W J H & Anholt, G E 2015, ' An admixture analysis of age of onset in agoraphobia ', Journal of Affective Disorders, vol. 180, pp. 112-115 . https://doi.org/10.1016/j.jad.2015.03.064
- Accession number :
- edsair.doi.dedup.....5e136b96a4eaf0ab7bf9d3b7f048f00a