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Predictors of Seizure Recurrence after Acute Symptomatic Seizures in Ischemic Stroke Patients
- Source :
- Neuroscience Journal, Neuroscience Journal, Vol 2019 (2019)
- Publication Year :
- 2019
- Publisher :
- Hindawi Limited, 2019.
-
Abstract
- Purpose. Seizure is a well-recognized complication of both remote and acute ischemic strokes. Predictors of seizure recurrence and epilepsy in patients with ischemic stroke who develop acute symptomatic seizures (ASyS) on continuous electroencephalography (cEEG) have not been well studied. Methods. We present a five-year retrospective study of acute and remote ischemic stroke patients who developed ASyS on cEEG. We then identified risk factors for the development of seizure recurrence. Results. Sixty-five patients with ischemic stroke and ASyS were identified and reviewed. All ASyS were noted to be nonconvulsive seizures. Clinical recurrence of seizures was identified in 19 of these patients (29.2%) at follow-up. Rate of seizure recurrence was higher in remote ischemic stroke patients (84.2%), compared to acute ischemic stroke patients (15.8%, p=0.0116, OR 0.17, 95% CI 0.049–0.65). Sharp waves/spikes on follow-up EEG significantly correlated with seizure recurrence (p=0.006, OR 0, 95% CI 0–0.3926). Patients discharged on ≥3 antiepileptic drugs (AEDs) were at a higher risk of having seizure recurrence (p=0.0015, OR 0.05, 95% CI 0.0089–0.37). Conclusion. We identified risk factors of seizure recurrence in patients with ASyS as remote ischemic stroke, requiring multiple AEDs, and the presence of sharp waves on follow-up EEG. This study highlights the usefulness of cEEG in evaluating patients with acute or remote strokes.
- Subjects :
- medicine.medical_specialty
Article Subject
medicine.diagnostic_test
business.industry
Retrospective cohort study
Symptomatic seizures
Electroencephalography
Seizure recurrence
medicine.disease
lcsh:RC321-571
03 medical and health sciences
Epilepsy
0302 clinical medicine
Internal medicine
mental disorders
Ischemic stroke
Cardiology
Medicine
In patient
030212 general & internal medicine
business
Complication
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
030217 neurology & neurosurgery
Research Article
Subjects
Details
- ISSN :
- 23144270 and 23144262
- Volume :
- 2019
- Database :
- OpenAIRE
- Journal :
- Neuroscience Journal
- Accession number :
- edsair.doi.dedup.....5e234b988a99af8bff7a84cbecd56c4c