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Validation of a symptoms questionnaire for benign prostatic hyperplasia
Validation of a symptoms questionnaire for benign prostatic hyperplasia
- Source :
- The Prostate. 21:247-254
- Publication Year :
- 1992
- Publisher :
- Wiley, 1992.
-
Abstract
- We developed a questionnaire to assess the effect of finasteride on symptoms of benign prostatic hyperplasia (BPH) by modifying that of Boyarsky (1977). To validate the questionnaire, a cohort study was conducted in 2 groups of patients with BPH and 3 control groups without BPH. The BPH groups were: (1) 34 patients before TURP (transurethral resection of the prostate), average age 68 years; (2) 65 patients after TURP, average age 68 years; (3) 40 patients after other nonserious nonurological surgery, average age 50 years; (4) 14 healthy non-BPH volunteers, average age 58 years; and (5) 73 healthy non-BPH volunteers, average age 37 years. The questionnaire was administered once to all subjects, and a subset responded to a second administration. Mean total symptoms scores (TSS) from the initial questioning were 6.4, 3.2, 2.9, 2.6, and 1.6 for the 5 groups, respectively (pooled SD = 3.3); mean total troublesome symptoms scores (TTSS) were 4.8, 2.1, 1.4, 1.1, and 0.6, respectively (pooled SD = 2.2). All other groups were significantly less symptomatic and troubled than the pre-TURP group, and all surgical groups were significantly more so than the younger volunteer group. These data demonstrate the discriminant validity of the questionnaire. Corroborating prior data [Gregg et al., 1990], responsiveness was shown by the 3.7-point mean TSS improvement in response to TURP, which was significantly different from the near-zero changes in the other groups. Reproducibility was shown by kappa statistics being nearly all greater than 0.75 and an intraclass correlation coefficient of 0.64; construct validity and reliability were demonstrated by correlation (r = 0.7) with a general urination problems question; and internal consistency was documented by Cronbach's alpha values of approximately 0.6. We conclude that this questionnaire is a useful and validated tool for assessing BPH symptoms.
- Subjects :
- Male
medicine.medical_specialty
Intraclass correlation
Urology
medicine.medical_treatment
Statistics as Topic
Prostatic Hyperplasia
urologic and male genital diseases
Severity of Illness Index
chemistry.chemical_compound
Cronbach's alpha
Surveys and Questionnaires
Internal medicine
medicine
Humans
Volunteer
Transurethral resection of the prostate
Gynecology
business.industry
Discriminant validity
Construct validity
Oncology
chemistry
Evaluation Studies as Topic
Finasteride
business
Cohort study
Subjects
Details
- ISSN :
- 10970045 and 02704137
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- The Prostate
- Accession number :
- edsair.doi.dedup.....5e35ee4fec4f6c0251baa3df77b9a154
- Full Text :
- https://doi.org/10.1002/pros.2990210308