Back to Search
Start Over
Pandrug-ResistantAcinetobacter baumanniiCausing Nosocomial Infections in a University Hospital, Taiwan
- Source :
- Emerging Infectious Diseases, Emerging Infectious Diseases, Vol 8, Iss 8, Pp 827-832 (2002)
- Publication Year :
- 2002
- Publisher :
- Centers for Disease Control and Prevention (CDC), 2002.
-
Abstract
- The rapid emergence (from 0% before 1998 to 6.5% in 2000) of pandrug-resistant Acinetobacter baumannii (PDRAB) was noted in a university hospital in Taiwan. To understand the epidemiology of these isolates, we studied 203 PDRAB isolates, taken from January 1999 to April 2000: 199 from 73 hospitalized patients treated at different clinical settings in the hospital and 4 from environmental sites in an intensive-care unit. Pulsed-field gel electrophoresis analysis and random amplified polymorphic DNA (RAPD) generated by arbitrarily primed polymerase chain reaction of these 203 isolates showed 10 closely related genotypes (10 clones). One (clone 5), belonging to pulsotype E and RAPD pattern 5, predominated (64 isolates, mostly from patients in intensive care). Increasing use of carbapenems and ciprofloxacin (selective pressure) as well as clonal dissemination might have contributed to the wide spread of PDRAB in this hospital.
- Subjects :
- Male
Acinetobacter baumannii
Microbiology (medical)
Genotype
Epidemiology
Taiwan
lcsh:Medicine
Microbial Sensitivity Tests
Drug resistance
Polymerase Chain Reaction
lcsh:Infectious and parasitic diseases
Disease Outbreaks
Microbiology
law.invention
law
Drug Resistance, Multiple, Bacterial
Intensive care
nosocomial infections
medicine
Humans
lcsh:RC109-216
Polymerase chain reaction
Cross Infection
Acinetobacter
biology
Research
lcsh:R
Drug Synergism
biology.organism_classification
Virology
Anti-Bacterial Agents
Electrophoresis, Gel, Pulsed-Field
RAPD
Ciprofloxacin
Infectious Diseases
Genes, Bacterial
Carrier State
Female
Pandrug-resistant
Acinetobacter Infections
medicine.drug
Subjects
Details
- ISSN :
- 10806059 and 10806040
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....5ec32758394850d252de742a045439a7