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Design and Synthesis of a [2.2]Paracyclophane‐based Planar Chiral Dirhodium Catalyst and its Applications in Cyclopropanation Reaction of Vinylarenes with α‐Methyl‐α‐Diazo Esters
- Source :
- Advanced synthesis & catalysis, 362 (16), 3431-3436
- Publication Year :
- 2020
- Publisher :
- John Wiley and Sons, 2020.
-
Abstract
- A planar chiral dirhodium paddlewheel complex Rh$_{2}$(S $_{p}$−PCP)$_{4}$ based on the [2.2]paracyclophane has been synthesized for the challenging cyclopropanation of venylarene derivatives with tert‐butyl α‐diazo propionates. The homobimetallic rhodium catalyst relies on the high steric demand and rigidity of [2.2]paracyclophane that favors the cyclopropanation of 1‐aryl substituted, 1,1‐disubstituted and benzannulated alkenes over β‐hydride migration at room temperature with high diastereoselectivity.
- Subjects :
- Chemistry & allied sciences
ddc:540
Subjects
Details
- Language :
- English
- ISSN :
- 16154150 and 16154169
- Database :
- OpenAIRE
- Journal :
- Advanced synthesis & catalysis, 362 (16), 3431-3436
- Accession number :
- edsair.doi.dedup.....5f2359507bfc47982e4e1010617c2991