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Bilateral malignant melanoma metastases to the internal auditory canal/cerebellopontine angle: surgical management and preservation of function
- Source :
- Journal of Neurosurgery. 108:803-807
- Publication Year :
- 2008
- Publisher :
- Journal of Neurosurgery Publishing Group (JNSPG), 2008.
-
Abstract
- âś“Although intracranial metastases of malignant melanomas are common, localization at the cerebellopontine angle (CPA) or in the internal auditory canal (IAC) is rare, and bilateral presentation especially so. We present the case of a 46-year-old Caucasian woman with bilateral IAC/CPA lesions and a prior history of malignant melanoma on the right leg. During preoperative investigations, the presence of the bilateral IAC/CPA lesions along with several radiologically identified lesions along the neural axis led to the suspicion that she had neurofibromatosis Type 2 despite her history of malignant melanoma and the lack of characteristic skin lesions and family history. Histopathological analysis of the resected lesion confirmed the intraoperative diagnosis of bilateral CPA malignant melanoma metastases. Surgical removal of the tumors via the retrosigmoid approach with preservation of normal bilateral facial nerve function and unilateral serviceable hearing, combined with control of the systemic disease, provided this patient with a near-normal quality of life for at least 42 months after the initial diagnosis of melanoma.
- Subjects :
- medicine.medical_specialty
Skin Neoplasms
Labyrinth Diseases
Cerebellopontine Angle
Metastasis
Lesion
medicine
Humans
Neurofibromatosis type 2
Cerebellar Neoplasms
Melanoma
Ear Neoplasms
medicine.diagnostic_test
business.industry
Cancer
Magnetic resonance imaging
General Medicine
Middle Aged
medicine.disease
Cerebellopontine angle
Magnetic Resonance Imaging
Facial nerve
Surgery
Ear, Inner
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 19330693 and 00223085
- Volume :
- 108
- Database :
- OpenAIRE
- Journal :
- Journal of Neurosurgery
- Accession number :
- edsair.doi.dedup.....5f71e98b64ea810e06d04b46146d79d1
- Full Text :
- https://doi.org/10.3171/jns/2008/108/4/0803