Additional file 8 of Growth hormone reduces aneuploidy and improves oocytes quality by JAK2-MAPK3/1 pathway in aged mice

Additional file 8: Figure S5. Effect of GH on the meiotic progression of aged oocytes in vitro.Representative time-lapse images of PBE kinetics in young, aged and GH + aged oocytes. Scale bar, 50 μm. PBE rate in young, aged, and GH + agedoocytes in vitro PBE kinetics in young, aged, and GH + agedoocytes post-GVBD. Interval from GVBD to PBE in young, aged, and GH + agedoocytes. Data are mean ± SEMs of at least three independent experiments. *p < 0.05.