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Non-halogenated new sesquiterpenes from Bornean Laurencia snackeyi
- Source :
- Natural product research. 31(3)
- Publication Year :
- 2016
-
Abstract
- Two new non-halogenated sesquiterpenes, snakeol (1) and snakediol (2) were isolated together with 9 known sesquiterpenes such as (R,Z)-33-dimethyl-5-methylene-4-(3-methylpenta-24-dien-1-yl)cyclohex-1-ene (3), palisol (4), pacifigorgiol (5), palisadin D (6), palisadin A (7), palisadin B (8), 5-acetoxypalisadin B (9), debromolaurinterol (10) and α-bromocuparane (11) from the red algae Laurencia snackeyi. The structures of two new metabolites were determined from their spectroscopic data (IR, 1D and 2D NMR and MS). Compounds 1, 2, 10 and 11 showed strong antibacterial activity against selected human clinical bacterial pathogens.
- Subjects :
- Magnetic Resonance Spectroscopy
Halogenation
Stereochemistry
Plant Science
Red algae
Sesquiterpene
01 natural sciences
Biochemistry
Laurencia
Analytical Chemistry
chemistry.chemical_compound
Palisadin B
Humans
biology
Molecular Structure
010405 organic chemistry
Organic Chemistry
Rhodomelaceae
biology.organism_classification
0104 chemical sciences
Laurencia snackeyi
Anti-Bacterial Agents
010404 medicinal & biomolecular chemistry
chemistry
Rhodophyta
Antibacterial activity
Two-dimensional nuclear magnetic resonance spectroscopy
Sesquiterpenes
Subjects
Details
- ISSN :
- 14786427
- Volume :
- 31
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Natural product research
- Accession number :
- edsair.doi.dedup.....5fa11039b45c3a0f19443a5772b3937d